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PEOPLE

Wes Sundquist, Director
Pamela Bjorkman
Debbie Eckert
Nels Elde
Adam Frost
Chris Hill
Tom Hope
​Janet Iwasa 
Grant Jensen
Michael Kay
Anthony Kossiakoff
Neil King
Walther Mothes
Elisabetta Viani Puglisi
Barbie Ganser-Pornillos
Greg Voth
Mark Yeager

Scientific Advisory Board

Collaborative Development Program Awardees

Tom Hope

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Hope’s laboratory studies the cell biology of HIV using advanced microscopy. These techniques include photobleaching and photoactivation to define the localization and mobility of HIV Gag and HIV receptors in living cells. Together with collaborators, Hope developed techniques for labeling HIV virions with the green fluorescent protein, thereby allowing individual virions to be followed by fluorescence microscopy in living cells. Using this technology, Hope’s group showed that HIV utilizes the microtubule network to traffic to the nucleus, that HIV infection is stimulated by dendritic cells through the formation of an infectious synapse, and that the antiviral action of the HIV restriction factor TRIM5a is mediated in multiple phases.

Tom Hope, PhD
Professor of Cell and Molecular Biology
Northwestern University Medical School
303 E. Chicago Avenue, Ward 8-140
Cell and Molecular Biology Department
Chicago, Illinois 60611
Phone: (312) 503-1360
Fax: (312) 503-7912
Email: thope@northwestern.edu
Web page: http://labs.feinberg.northwestern.edu/hope/
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